Your new company
You'll be joining a global biopharmaceutical company advancing innovative therapies for immune-mediated diseases. You'll become part of a highly collaborative translational research team supporting programmes from late discovery through early clinical development, helping to generate the human biology insights needed to inform key development decisions across multiple immunology drugs.

Your new role
As a Senior Scientist, you will use human-derived systems and translational models to support the progression of multiple clinical-stage therapeutic programmes in immunology and immune-mediated disease.
This is initially a 12 month contract that is very likely to extend and is mainly lab-based with some work from home flexibility.

Key responsibilities include:

• Designing and running complex in-vitro and ex-vivo human cell and tissue models to investigate disease biology and therapeutic mechanisms of action
• Establishing translational assays using primary human cells, tissue-resident cell systems, co-cultures, and advanced functional models
• Generating and interpreting preclinical data to support patient population selection, proof-of-concept strategies, and clinical programme decision-making
• Producing and analysing experimental readouts including flow cytometry, protein analysis, gene expression, RNA-based assays, and related immunology techniques
• Integrating biological findings with larger datasets to develop mechanistic understanding and support translational insights
• Collaborating closely with multidisciplinary teams across research, translational medicine, and clinical development to deliver project milestones

What you'll need to succeed
A successful candidate will bring strong laboratory-based immunology expertise together with experience working in translational research environments as well as:

• A PhD (or equivalent experience) in Immunology, Cell Biology, Translational Biology, or a related discipline
• Strong hands-on experience establishing and running functional in vitro (and/or ex vivo) assays using human cells and tissues
• Deep understanding of immunology and/or stromal biology, ideally within immune-mediated or tissue-remodelling diseases
• Experience generating and interpreting complex biological datasets and translating findings into actionable conclusions
• Proven ability to work independently and deliver high-quality experimental data in a fast-paced research environment
• Experience with RNAseq, single-cell, spatial transcriptomics, proteomics, CRO management, or drug discovery programmes would be advantageous, as would any experience with transcriptomic or genomic data analysis
• The right to work in the UK until at least November 2027 (preferably beyond this) as no sponsorship is available for this role

What you'll get in return
The chance to make a real impact on several of the company's clinical-stage programmes and influence key development decisions, as well as a good pay rate and some home working flexibility.

What you need to do now
If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call us now.
If this job isn't quite right for you but you are looking for a new position, please contact us for a confidential discussion on your career.

Keywords: R&D, Immunology, Scientist, Senior, Research, Pharmaceutical, Translational, Biology, Inflammation, Immune, Stromal, Cell, Culture, Tissue, Drug, Human, Assay, Ex-vivo, In-vitro, Cytometry, Flow, RNAseq, Transcriptomics, Proteomics, Biomarkers, Therapeutics, Development, Immunofluorescence, Gene, Expression, Clinical, Discovery, Mechanism