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Principal Computational Biologist -BioTech- Alzheimer's disease

Robert Walters

London · Posted 2 Nov 2026 · 3 applicants

Permanent
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Our client is a seed stage TechBio (£2.7m funding) building a platform solution for identifying drug targets for neurological diseases with in-vitro validation.

About the role:

Lead computational biology strategy for target identification in neurology, combining hands-on pipeline development with scientific leadership and cross-functional collaboration.

Key Responsibilities
  • Lead QTL mapping and integrate multi-omics / functional genomics for target prioritisation
  • Build and own multi-omics pipelines (QC, normalisation, analysis)
  • Collaborate with ML engineers on model design, feature selection, training, evaluation, interpretation
  • Define and maintain knowledge graph schemas and computational evidence layers
  • Translate outputs into biological hypotheses and support in vitro validation & assay design
Requirements
  • PhD + 3 to 5 years in computational biology (multi-omic target discovery)
  • Strong Python, R, HPC/cloud computing
  • Experience with transcriptomics, proteomics, epigenomics
  • Proven work in target discovery, prioritisation, in silico validation
  • Strong statistical analysis & data visualisation
  • Neurology / neurodegeneration experience (preferred)
  • Biotech/pharma background + strong communication & problem-solving
Summary

Hands-on role driving multi-omics target discovery, integrating ML and data platforms, and working closely with experimental teams in a neurology-focused biotech.

Robert Walters Operations Limited is an employment business and employment agency and welcomes applications from all candidates

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